I'm all at sea.
Fat chance.
I'm throwing in the towel.
Where do I go from here?
We've had it.
It's the end of the world for me.
No such luck!
I've got a lot on my mind.[@more@]That's the way it goes.
I'm downhearted.
I'm on my last legs.
It's fate./It's doomed./It is my destiny.